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KMID : 0376419800040010217
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Chonbuk University Medical Journal
1980 Volume.4 No. 1 p.217 ~ p.220
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Effect of eletrical stimulation of the afferent vagal nerve on the elevation of the blood pressure of the rabbit
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Abstract
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In order to clarify the mechanism which the elevation of the blood pressure by vagal afferent electrical stimulation, some pharmacological analysis was made.
1. Stimulation: of vagal afferent nerve caused depressor response, initial depressor effect followed by pressor response or pressor effect according to the applied Hertz and other factors.
2. Pressor effect of the stimulation was inhibited by intraventricular opilon or prazosin which drug was*kupposed as postsynaptic adrenergic blocking agent.
3. Pressor effect of the stimulation was potentiated by intraventricular yohimbine or piperoxan whicli drug was supposed as presynaptic adrenergic blocking agent.
From the above results, it is suggested that central postsynaptic adrenergic mechanismn is involved in the. elevation of blood pressure by electrical stimulation "of afferent vagal nerve of the rabbit,
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